Loading...

Please wait while we retrieve your documents

ARCHIVES

Original Article

The Role of the Pharmacist in the Reduction of Medication Errors: A Narrative Review of Interventions across the Medication Use Process

Raghavendra S. Hegde1

1 Department of Pharmacy Practice, Hanagal Shri Kumareshwar College of Pharmacy, B.V.V. Sangha’s, Bagalkote,Karnataka, India.

Published Online: May-August 2026

Pages: 07-13

Cite this article

No Doi

Abstract

Medication errors remain among the most frequent and most preventable causes of avoidable harm in health care, occurring at every stage of the medication use process — prescribing, transcribing, dispensing, administration and monitoring. Because the pharmacist is the only professional whose training spans the whole of this pathway, the profession occupies a uniquely favourable position from which to intercept error before it reaches the patient. This review synthesises the evidence on pharmacist-led interventions for medication error reduction and organises it around the points in the medication use process at which pharmacists act. Prescribing-stage interventions — ward-based clinical pharmacy, participation in physician rounds and prescription review — consistently produce the largest absolute reductions in error, since the prescribing stage generates the greatest share of errors and permits interception before any drug is administered. Medication reconciliation at admission, transfer and discharge addresses the transitions of care at which discrepancies concentrate. Dispensing-stage safeguards, antimicrobial and anticoagulation stewardship, patient counselling and pharmacovigilance participation each contribute further. Technology, including computerised prescriber order entry, clinical decision support, barcode-assisted administration and automated dispensing, amplifies pharmacist effectiveness but introduces its own error modes and cannot substitute for professional judgement. Sustained benefit depends less on any single intervention than on the surrounding conditions: adequate pharmacist-to-bed ratios, a non-punitive reporting culture, interdisciplinary credibility and integration into the clinical team rather than confinement to the dispensary. Barriers relevant to resource-limited settings — staffing shortfalls, restricted access to drug information, hierarchical professional relationships and the absence of formal error reporting systems — are examined alongside practical strategies to address them. The evidence supports a clear conclusion: pharmacists reduce medication errors substantially when positioned within the clinical team, and the principal obstacle is no longer proof of effectiveness but the structural investment required to deploy them.

References

  • 1. National Coordinating Council for Medication Error Reporting and Prevention. About medication errors: NCC MERP taxonomy and index for categorizing medication errors. Rockville: NCC MERP.

  • 2. World Health Organization. Medication Without Harm: WHO Global Patient Safety Challenge. Geneva: World Health Organization; 2017.

  • 3. Aspden P, Wolcott J, Bootman JL, Cronenwett LR, editors; Institute of Medicine Committee on Identifying and Preventing Medication Errors. Preventing medication errors. Washington DC: National Academies Press; 2007.

  • 4. Ferner RE, Aronson JK. Clarification of terminology in medication errors: definitions and classification. Drug Saf. 2006;29(11):1011–1022.

  • 5. Bates DW, Cullen DJ, Laird N, Petersen LA, Small SD, Servi D, et al. Incidence of adverse drug events and potential adverse drug events: implications for prevention. JAMA. 1995;274(1):29–34.

  • 6. Reason J. Human error: models and management. BMJ. 2000;320(7237):768–770.

  • 7. Leape LL, Cullen DJ, Clapp MD, Burdick E, Demonaco HJ, Erickson JI, et al. Pharmacist participation on physician rounds and adverse drug events in the intensive care unit. JAMA. 1999;282(3):267–270.

  • 8. Kaboli PJ, Hoth AB, McClimon BJ, Schnipper JL. Clinical pharmacists and inpatient medical care: a systematic review. Arch Intern Med. 2006;166(9):955–964.

  • 9. Christensen M, Lundh A. Medication review in hospitalised patients to reduce morbidity and mortality. Cochrane Database Syst Rev. 2016;(2):CD008986.

  • 10. Movva R, Jampani A, Nathani J, Pinnamaneni SH, Challa SR. A prospective study of incidence of medication-related problems in general medicine ward of a tertiary care hospital. J Adv Pharm Technol Res. 2015;6(4):190–194.

  • 11. Leopoldino RD, Santos MT, Costa TX, Martins RR, Oliveira AG. Drug-related problems in the neonatal intensive care unit: incidence, characterization and clinical relevance. BMC Pediatr. 2018;18(1):134.

  • 12. Mekonnen AB, McLachlan AJ, Brien JE. Effectiveness of pharmacist-led medication reconciliation programmes on clinical outcomes at hospital transitions: a systematic review and meta-analysis. BMJ Open. 2016;6(2): e010003.

  • 13. Kwan JL, Lo L, Sampson M, Shojania KG. Medication reconciliation during transitions of care as a patient safety strategy: a systematic review. Ann Intern Med. 2013;158(5 Pt 2):397–403.

  • 14. Institute for Safe Medication Practices. ISMP list of high-alert medications in acute care settings. Horsham: ISMP.

  • 15. Nkansah N, Mostovetsky O, Yu C, Chheng T, Beney J, Bond CM, et al. Effect of outpatient pharmacists' non-dispensing roles on patient outcomes and prescribing patterns. Cochrane Database Syst Rev. 2010;(7):CD000336.

  • 16. Nuckols TK, Smith-Spangler C, Morton SC, Asch SM, Patel VM, Anderson LJ, et al. The effectiveness of computerized order entry at reducing preventable adverse drug events and medication errors in hospital settings: a systematic review and meta-analysis. Syst Rev. 2014; 3:56.

  • 17. Poon EG, Keohane CA, Yoon CS, Ditmore M, Bane A, Levtzion-Korach O, et al. Effect of bar-code technology on the safety of medication administration. N Engl J Med. 2010;362(18):1698–1707.

Citations

Raghavendra S. Hegde,“The Role of the Pharmacist in the Reduction of Medication Errors: A Narrative Review of Interventions Across the Medication Use Process”, Indian Journal of Clinical and Medical Research, Volume 01, Issue 02, May-August 2026, PP: 07-13.

Article Metrics

239
Views
0
Citations
PlumX Metrics PlumX Metrics
Dimension Dimension

Licensing

© 2026 The Author(s). Published by Fifth Dimension Research Publication.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/4.0/ ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.