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Year 2026 · Volume 1 · Issue 3

Case Report

Terlipressin-Induced Toe and Foot Ischemia in Liver Transplant Patients

Dr. Manpreet Kaur1
1 Clinical Pharmacologist, Outpatient Department, Shahkot, Jalandhar, Punjab, India.

Published Online: September-December 2026

Pages: 01-02

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Abstract

Terlipressin is a medication commonly used to support blood pressure and kidney function in end-stage liver disease. While effective, its strong blood vessel-narrowing properties can sometimes lead to reduced blood supply in the fingers or toes. We present the case of a 54-year-old male liver transplant recipient who developed bluish discoloration and coldness in his feet during continuous terlipressin infusion. Stopping the medication immediately, alongside supportive care, led to a full recovery and normal limb health.

References

  • 1. Akdemir, N. Ü. Postoperative hemodynamic stabilization with terlipressin: A case of. DergiPark.

  • 2. Ata, F., Ahmed Osman, A. M. E., Dakhlia, I., & Zahid, M. (2020). Terlipressin-induced foot ischemia. Clinical Case Reports, 9(1), 592-593.

  • 3. Basheer, A., Shaleem, M., & Karoli, R. (2018). Cutaneous ischaemia following terlipressin therapy for hepatorenal syndrome: A case report

  • and review of literature. Journal of Clinical and Diagnostic Research, 12(3), OD08-OD10.

  • 4. Jasiewicz, P. Intraoperative terlipressin during liver transplantation is associated with reduced vasoactive requirements and lower

  • postoperative troponin release. MDPI, 15(8), 2916.

  • 5. Sundriyal, D., Kumar, N., Patnaik, I., Kamble, U. (2013). Terlipressin induced ischaemia of skin. BMJ Case Reports, 2013:bcr2013010050.

Citations

Dr. Manpreet Kaur, “Terlipressin-Induced ToeandFootIschemia in Liver Transplant Patients”, Indian Journal of Clinical and Medical Research, Volume 01, Issue 03, September-December 2026, PP: 01-02.

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Licensing

© 2026 The Author(s). Published by Fifth Dimension Research Publication.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/4.0/ ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

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