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Racial Disparities in Access to PI3K Inhibitors Despite Comparable Mutation Burden: Addressing Data Gaps in Early-Onset and Rare Cancers
Authors
1 PhD Scholar, Faculty of medical biochemistry, Adichunchanagiri University, B G Nagara, India. 2 Professor and Head, Department of biochemistry, BGS Medical College and Hospital Nagnur, Adichunchanagiri University, India.
Article Information
- DOI
- No Doi
- Published In
- Year 2026 · Volume 1 · Issue 1
- Published Online
- January-April 2026
- Pages
- 01-07
- Article Type
- Review Article
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33. Spratt DE, et al. JAMA Oncol. 2019;5(2):273-278.
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47. Patel NM, et al. NPJ Precis Oncol. 2021;5(1):77
2. Cancer Genome Atlas Research Network. Nature. 2012;487(7407):330- 337.
3. André F, et al. N Engl J Med. 2019;380(20):1929-1940. (SOLAR-1 trial)
4. Juric D, et al. N Engl J Med. 2023;389(7):620-632. (INAVO120 trial)
5. Zehir A, et al. Nat Med. 2017;23(6):703-713.
6. TCGA Pan-Cancer Analysis. Cell. 2018;173(2):407-419.
7. Bychkovsky A, et al. J Clin Oncol. 2022;40(16_suppl):e12500.
8. Singleton D, et al. JAMA Netw Open. 2023;6(5):e2313612.
9. NCCN Guidelines: Breast Cancer. Version 8.2024.
10. ESMO Guidelines: Endometrial Cancer. Ann Oncol. 2022;33(7):707-726.
11. Phipps AI, et al. J Natl Cancer Inst. 2019;111(11):1183-1191.
12. Boland PM, et al. JCO Precis Oncol. 2021;5:PO.20.00485.
13. Pietrantonio F, et al. J Clin Oncol. 2019;37(27):2437-2446.
14. Dogan S, et al. Mod Pathol. 2019;32(10):1393-1404.
15. Spratt DE, et al. JAMA Oncol. 2019;5(2):273-278.
16. Popejoy AB, Fullerton SM. Genome Biol. 2016;17(1):157.
17. SEER Cancer Statistics Review 1975-2020. National Cancer Institute. 2023.
18. Unger JM, et al. JAMA Oncol. 2016;2(8):970-975.
19. Fruman DA, et al. Cell. 2017;169(1):11-15.
20. Castel P, et al. Nat Rev Drug Discov. 2019;18(10):819-820.
21. Kandoth C, et al. Nature. 2013;502(7471):423-429.
22. Zehir A, et al. Nat Med. 2017;23(6):703-713.
23. AACR GENIE Consortium. Cancer Discov. 2023;13(7):1527-1538.
24. André F, et al. N Engl J Med. 2019;380(20):1929-1940.
25. Juric D, et al. N Engl J Med. 2023;389(7):620-632.
26. Matulonis UA, et al. J Clin Oncol. 2023;41(16_suppl):3003.
27. Hyman DM, et al. Cancer Discov. 2021;11(4):936-949.
28. Elosegui-Artola A, et al. Nat Cell Biol. 2020;22(11):1281-1292.
29. Bychkovsky A, et al. J Clin Oncol. 2022;40(16_suppl):e12500.
30. Ruiz MP, et al. Gynecol Oncol. 2021;162(2):297-304.
31. Singleton D, et al. JAMA Netw Open. 2023;6(5):e2313612.
32. Li Y, et al. JAMA Oncol. 2021;7(10):1489-1498.
33. Spratt DE, et al. JAMA Oncol. 2019;5(2):273-278.
34. Unger JM, et al. J Natl Cancer Inst. 2019;111(11):1183-1191.
35. Hanker LC, et al. Cancer Discov. 2020;10(10):1526-1541.
36. Ugai T, et al. Nat Rev Clin Oncol. 2022;19(5):293-307.
37. Phipps AI, et al. J Natl Cancer Inst. 2019;111(11):1183-1191.
38. Malone KE, et al. J Natl Cancer Inst. 2010;102(12):875-888.
39. Partridge AH, et al. J Clin Oncol. 2023;41(16_suppl):TPS629.
40. Yurgelun MB, et al. J Clin Oncol. 2017;35(5):439-445.
41. Pietrantonio F, et al. J Clin Oncol. 2019;37(27):2437-2446.
42. Dogan S, et al. Mod Pathol. 2019;32(10):1393-1404.
43. cBioPortal for Cancer Genomics. Accessed Oct 2024.
44. Subbiah V, et al. J Clin Oncol. 2021;39(15_suppl):3002.
45. NCI Cancer Moonshot Progress Report. 2023.
46. Muss HB, et al. J Geriatr Oncol. 2022;13(1):1-7.
47. Patel NM, et al. NPJ Precis Oncol. 2021;5(1):77
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